Jessica Biel and Jimmy Fallon try to guess Justin Timberlake's responses to a series of random questions in a competition to see who really knows him best.

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The Tonight Show Starring Jimmy Fallon features hilarious highlights from the show including: comedy sketches, music parodies, celebrity interviews, ridiculous games, and, of course, Jimmy's Thank You Notes and hashtags! You'll also find behind the scenes videos and other great web exclusives.

Best Friends Challenge with Justin Timberlake and Jessica Biel
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#BestFriendsChallenge
#JustinTimberlake
#JessicaBiel

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